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Tissue Factor: Recombinant Human Tissue Factor Fully functional Tissue Factor for coagulation research Tissue Factor (TF) is a cell-surface protein present on endothelial cells and monocytes which is involved in coagulation and inflammation. TF is the primary initiator of the blood coagulation protease cascade functioning as a receptor and cofactor for the extrinsic tenase complex. Product TF-263 is full length human tissue factor, produced in a recombinant eukaryotic expression system. Product TF-243 is a truncated human tissue factor, produced in a recombinant eukaryotic expression system. The 263 amino acid tissue factor protein is comprised of an extracellular, a transmembrane domain and a cytoplasmic domain. The 243 form is similar but lacks the cytoplasmic domain. The relipidated 243 and 263 forms of the molecule are fully functional in coagulation assays and displays comparable specific activity. View Product Sheet (TF 243)
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